制何首乌
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制何首乌中主要药效/毒效成分的生物药剂学分类系统评价研究
目的对制何首乌5种主要药效/毒效成分没食子酸、大黄素、二苯乙烯苷、大黄素甲醚和大黄素-8-O-β-D-葡萄糖苷进行生物药剂学分类系统(BCS)研究。方法分别采用平衡溶解度法和外翻肠囊法研究各代表成分的...

《中草药》 2020年13期关键词: "制何首乌"," 溶解度"," 渗透性"," 生物药剂学分类系统"," 药效"," 毒效"," 没食子酸"," 大黄素"," 二苯乙烯苷"," 大黄素甲醚"," 大黄素-8-O-β-D-葡萄糖苷"," 平衡溶解度法"," 外翻肠囊法"," 相关性"," 蒽醌"," 假阳性"," 体外生物利用度"," 体内吸收"," 安全性" 收藏